In terms of removing negatives, there are only a few I really bother with - such as Kleptomania, Curious, and Antsy (which causes idle heroes to generate stress at the Hamlet). Outside of that, you rarely - if ever - need three cells available at one time. That's pretty much the only reason I level up the Sanitarium at all, because having 3 cells + free week = three heroes with a locked positive + removed negative at no gold cost. In terms of locking quirks, I never honestly bother unless (a) I'm stinking rich and/or into the end-game, or (b) when you activate the sanitarium-related town event to make quirk management free for a week. It's best to think of it like added specialization. You'll never do huge damage in one go, but by stacking Blight effects you can end up doing over a dozen damage to an enemy every turn.The best combat stats across the board are speed and accuracy, so it's never a bad idea to maintain quirks that are related to those - at least when it comes to specific heroes. The Plague Doctor's main priority is keeping their team alive, and if everybody's fine, inflicting various status effects on the bigger enemies that wear them down and tax their Deathblow Resistance saves. Allies struggling to keep their blood inside them? Battlefield Medicine will pick them up.

Being attacked at range by artillery-focused foes? Trigger Blinding Gas to cripple their accuracy. Opposition got their own healers? Throw poison at the back two ranks. Big enemy? Blight them and watch their health drain. Frankly, adventuring without a Plague Doctor feels ridiculous, as their extreme versatility means they have something for every situation. Strategy: The Plague Doctor is your main support class, healing allies of both damage and afflictions while lobbing toxic explosives at the enemy that Blight and Blind them. Pros: Healing, status cures, status afflictions, ranged attacksĬons: Low health, poor front row fighter, does damage over time rather than quicklyĬould be replaced by: Occultist, but not really - the Plague Doctor's too good to swap out

Darkest dungeon jester best skills